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Furthermore, some DPP-4 inhibitors have specific features that make them safe to use in patients with CKD without the need for dose adjustment and are therefore necessary in this subset [34]

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All authors approved the final version of the manuscript

These consistent benefits have been rapidly translated into practice

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NMN and NR are commonly studied in relation to nicotinamide-associated metabolic pathways, whereas 5-Amino-1MQ acts through selective inhibition of NNMT